Dimethyl Sulfoxide → HCID 86735137, compound

HRID 972874Notes

Reaction equation

HRID 972874 reaction equation
ClC1C=CC(O[C:9]([N:11]2[CH2:15][CH2:14][N:13](C)[C:12]2=[C:17]([N+:28]([O-:30])=[O:29])[C:18]([O:20][C:21]2[CH:26]=[CH:25][C:24]([Cl:27])=[CH:23][CH:22]=2)=[O:19])=O)=CC=1.C(=O)([O-])[O-].[Na+].[Na+].CS(C)=O>O>[CH3:9][N:11]1[CH2:15][CH2:14][NH:13][C:12]1=[C:17]([N+:28]([O-:30])=[O:29])[C:18]([O:20][C:21]1[CH:26]=[CH:25][C:24]([Cl:27])=[CH:23][CH:22]=1)=[O:19]

Participants

5

Reactant 3

HCID 679Dimethyl SulfoxideHCID 10340Sodium CarbonateHCID 53733395HCID 53733395, compound

Product 1

HCID 86735137HCID 86735137, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

A stirred mixture of 3.62 g of 2A, 1.19 g of sodium carbonate, 20 ml of dimethyl sulfoxide, and 4 ml of water was kept at 100° C. for 1.5 hours. The mixture was cooled to room temperature and diluted with 10 ml of water. After ice-bath cooling, a white solid, 2, m.p.: 211°-212° (with decomposition) was isolated by filtration.

Workup

  1. temperatureAfter ice-bath cooling
  2. customa white solid, 2, m.p.: 211°-212° (with decomposition) was isolated by filtration

Sources & evidence

ORD record
ord-864605a402a14e03b4753d6bcf011f3f
Source dataset
uspto-grants-1977_10
Patent number
US04053623

Reaction notes

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