HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Bromide → HCID 21403016, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | α-(4-Fluorophenyl)-α-methyl-4-pyridinemethanol | HCID 21403012 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 21403016 | HCID 21403016 | — |
Reaction Steps
The starting material is prepared as follows: A mixture of 15 g of 4-(α-hydroxy-α-methyl-4-fluorobenzyl)- pyridine, 8.2 ml of benzyl bromide and 100 ml of acetonitrile is refluxed overnight. The solvent is evaporated and the residue recrystallized from isopropanol-diethyl ether, to yield the desired 1-benzyl-4-(α-hydroxy-α-methyl-4-fluorobenzyl)-pyridinium bromide melting at 175° with decomposition.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04054570 |
| Source dataset | uspto-grants-1977_10 |
| ORD ID | ord-27ce7d95d84c46169c0cf62b5d8df5de |
| Source note | uspto-grants-1977_10 |