2-(Methylamino)acetaldehyde → HCID 20357129, compound

HRID 972926Notes

Reaction equation

HRID 972926 reaction equation
[CH3:1][C:2]1[CH:3]=[CH:4][C:5]2[S:9][C:8]([N:10]=[C:11]=[O:12])=[N:7][C:6]=2[CH:13]=1.[CH3:14][NH:15][CH2:16][CH:17]=[O:18]>C1C=CC=CC=1>[CH3:14][N:15]([CH2:16][CH:17]=[O:18])[C:11]([NH:10][C:8]1[S:9][C:5]2[CH:4]=[CH:3][C:2]([CH3:1])=[CH:13][C:6]=2[N:7]=1)=[O:12]

Participants

4

Reactant 2

HCID 133161322-(Methylamino)acetaldehydeHCID 450774585-Methylbenzothiazol-2-yl isocyanate

Product 1

HCID 20357129HCID 20357129, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

5-Methylbenzothiazol-2-yl isocyanate dimer (0.1 mole), the dimethyl acetal of 2-methylaminoacetaldehyde (0.2 mole) and benzene (100 ml) are charged into a glass reaction vessel equipped with a mechanical stirrer and thermometer. The reaction mixture is stirred at ambient temperatures for a period of about one hour. After this time the reaction mixture is filtered, and the filtrate is stripped of solvent to yield the desired product the dimethyl acetal of 2-[1-methyl-3-(5-methylbenzothiazol-2-yl)ureido]acetaldehyde as the residue.

Workup

  1. customequipped with a mechanical stirrer
  2. filtrationAfter this time the reaction mixture is filtered

Sources & evidence

ORD record
ord-c3470db62485488a9eb3719143da610d
Source dataset
uspto-grants-1977_10
Patent number
US04054574

Reaction notes

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