Water → HCID 70636775, compound

HRID 972947Notes

Reaction equation

HRID 972947 reaction equation
[N:1]([CH:4]1[CH2:22][CH2:21][N:7]2[C:8]3[CH:20]=[CH:19][CH:18]=[CH:17][C:9]=3[CH2:10][C:11]3[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=3[CH:6]2[CH2:5]1)=[N+]=[N-].[H-].[H-].[H-].[H-].[Li+].[Al+3].O>CCOCC>[NH2:1][CH:4]1[CH2:22][CH2:21][N:7]2[C:8]3[CH:20]=[CH:19][CH:18]=[CH:17][C:9]=3[CH2:10][C:11]3[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=3[CH:6]2[CH2:5]1

Participants

5

Reactant 3

HCID 962WaterHCID 21226445Aluminium lithium hydrideHCID 86733598HCID 86733598, compound

Product 1

HCID 70636775HCID 70636775, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

4 g of 2-azido-1,2,3,4,10,14b-hexahydro-pyridino[1,2-a]-dibenzo[c,f]-azepine (axial) is added to a suspension of 3 g of LiAlH4 in dry ether. The mixture obtained is heated for 1 hour, and after that cooled down. Then 12 ml of water are added to the mixture dropwise, whereby an inorganic precipitate is formed. The inorganic residue is removed by filtration after which the filtrate is evaporated to dryness.

Workup

  1. customThe mixture obtained
  2. temperatureis heated for 1 hour
  3. temperatureafter that cooled down
  4. customwhereby an inorganic precipitate is formed
  5. customThe inorganic residue is removed by filtration after which the filtrate
  6. customis evaporated to dryness

Sources & evidence

ORD record
ord-9598ca09879e4f508b97927549ff63f0
Source dataset
uspto-grants-1977_10
Patent number
US04054572

Reaction notes

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