HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexene → Ethyl 2-[(3-amino-2-cyanophenyl)amino]-2-oxoacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexene | HCID 8079 | — |
| Reactant | HCID 12715758 | HCID 12715758 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Ethyl 2-[(3-amino-2-cyanophenyl)amino]-2-oxoacetate | HCID 12715740 | — |
Reaction Steps
The title compound is prepared by reduction of [3-nitro-2-cyanophenylamino]oxoacetic acid ethyl ester with 10% Pd. on charcoal and with cyclohexene in ethanol according to the procedure of I. D. Entwistle and R. A. W. Johnstone, J. Chem. Soc., Perkin I. 1300 (1975). The crude product is chromatographed on silica gel with chloroform and recrystallized from ethanol, m.p. 133°-136° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04054591 |
| Source dataset | uspto-grants-1977_10 |
| ORD ID | ord-0db0fc8397e54c9485d0e0d7ea338c79 |
| Source note | uspto-grants-1977_10 |