HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diazomethane → 2-(5H-dibenzo[a,d]cyclohepten-5-on-2-yl)propionic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diazomethane | HCID 9550 | — |
| Reactant | 5H-Dibenzo(a,d)cycloheptene-2-acetic acid, alpha-methyl-5-oxo- | HCID 173910 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 2-(5H-dibenzo[a,d]cyclohepten-5-on-2-yl)propionic acid methyl ester | HCID 12398825 | — |
Reaction Steps
5.0 G. of 2-(5H-dibenzo[a,d]cyclohepten-5-on-2-yl)propionic acid (preparation described infra) is suspended in 50 ml. of dioxane, added to excess ethereal diazomethane and stirred until dissolution is complete and evaporated to dryness. Purification as in part A on silica gel affords a nearly quantitative yield of 2-(5H-dibenzo[a,d]cyclohepten-5-on-2-yl)propionic acid methyl ester as in part A.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04054579 |
| Source dataset | uspto-grants-1977_10 |
| ORD ID | ord-e44a3f863b1a402682e4483b7b4ba08f |
| Source note | uspto-grants-1977_10 |