Potassium Carbonate → HCID 20203317, compound

Participants

Reaction Steps

186 g (2.2 moles) of O-methylhydroxylamine hydrochloride, dissolved in 322 ml of water, were added dropwise at 10° C to 322 g (2.32 moles) of potassium carbonate dissolved in 276 ml of water. 340 g (1.84 moles) of 2-nitrobenzoyl chloride were added dropwise to this mixture. After stirring the batch for one hour, the residue was filtered off and was suspended in lukewarm water in order to dissolve the admixed potassium chloride. The solid constituents were again filtered off and washed with water. 192 g (53% of theory) of N-methoxy-2-nitro-benzhydroxamic acid were obtained as a slightly granular beige-colored powder of melting point 104° C (which can be recrystallized from ethyl acetate). ##STR26##

Provenance & Evidence