2,2-Diethoxyethylamine → HCID 12707055, compound

Participants

Reaction Steps

1-[N-(3,5-dibenzyloxybenzyl)-N-p-tosyl-amino]-2,2-diethoxyethane (VI) is readily obtainable. For example, said compound (VI) is prepared by condensing 3,5-dibenzyloxybenzaldehyde with 1-amino-2,2-diethoxyethane at 60° to 100° C, reducing the resultant 1-[N-(3,5-dibenzyloxybenzylidene)amino]-2,2-diethoxyethane with sodium borohydride in ethanol under refluxing to give 1-[N-(3,5-dibenzyloxybenzyl)amino]-2,2-diethoxyethane, and then reacting said product with p-tosyl chloride in pyridine under ice-cooling.

Provenance & Evidence