HCID 12707063, compound → HCID 12707067, compound

Participants

Reaction Steps

0.2 g of 5.7-dibenzyloxy-1-(3,4,5-trimethoxybenzyl)-isoquinoline is dissolved in 250 ml of ethanol, and 0.05 g ot 10% palladium-carbon is added thereto. The mixture is shaken at 25° C in a hydrogen atmosphere. After the hydrogen uptake is completed, the catalyst is removed by filtration. The filtrate is evaporated to remove solvent. 0.125 g of 5,7-dihydroxy-1-(3,4,5-trimethoxybenzyl)-isoquinoline is thereby obtained as a crude product. Yield: 95% M.p. 270° - 275° C (decomp.) (recrystallized from ethanol).

Provenance & Evidence