Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 973044생성일: 2026년 10월 25일
Trifluoroacetic acid → Ethyl 6-ethyl-3,4-dihydro-5-hydroxy-4-oxothieno[2,3-d]PYRIMIDINE-2-CARBOXYLATE
https://huagongshe.com/reaction/973044
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Trifluoroacetic acid | HCID 6422 | — |
| 반응물 | Tetrafluoroborate | HCID 26255 | — |
| 반응물 | Ethyl 5-amino-6-ethyl-3,4-dihydro-4-oxothieno[2,3-d]PYRIMIDINE-2-CARBOXYLATE | HCID 12516925 | — |
| 반응물 | Potassium trifluoroacetate | HCID 23662811 | — |
| 생성물 | Ethyl 6-ethyl-3,4-dihydro-5-hydroxy-4-oxothieno[2,3-d]PYRIMIDINE-2-CARBOXYLATE | HCID 23330393 | — |
반응 단계
The diazonium fluoroborate salt is prepared as in Procedure 63 from the amino compound produced in Procedure 51 yielding 0.03 mole of the required idazonium fluoborate. The latter is added in one portion to a solution of 0.03 mole of potassium trifluoroacetate in 13 ml. of trifluoroacetic acid at 0° C. The mixture is stirred at 25° C. for 1 hour and then refluxed overnight. The trifluoroacetic acid is evaporated in vacuo to give a residue which is triturated with water and filtered to give the desired product.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04054656 |
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| 출처 데이터셋 | uspto-grants-1977_10 |
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| ORD ID | ord-2d90e88b0aae47a48537ed6a9b4507da |
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| 출처 메모 | uspto-grants-1977_10 |
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