Isopropyl isocyanate → HCID 13306745, compound

Participants

Reaction Steps

To 30 ml. of toluene were added 0.8 g of 2-nitroisonicotinamide and 1.7 g. of isopropyl isocyanate, and the mixture was refluxed for 6 hours. The reaction mixture was cooled and filtered removing 0.4 g. of the insoluble starting material. The filtrate was concentrated, and the residue was purified by silica gel chromatography and recrystallized from ethyl acetate - n-hexane to yield 0.08 g. of the desired product.

Provenance & Evidence