Acetic Acid → 2-(4-methylphenyl)-2-oxoethyl acetate

HRID 973079Notes

Reaction equation

[CH3:1][C:2]1[CH:11]=[CH:10][C:5]([C:6](=[O:9])[CH2:7]Br)=[CH:4][CH:3]=1.[C:12]([OH:15])(=[O:14])[CH3:13]>>[C:12]([O:15][CH2:7][C:6]([C:5]1[CH:10]=[CH:11][C:2]([CH3:1])=[CH:3][CH:4]=1)=[O:9])(=[O:14])[CH3:13]

Participants

Reactant 2

HCID 176Acetic Acid

HCID 692722-Bromo-4'-methylacetophenone

Product 1

HCID 51513322-(4-methylphenyl)-2-oxoethyl acetate

Procedure

Following the procedure of Example 1, 5 grams of 4-methylphenacyl bromide reacted with 5 grams of acetic acid to obtain 4-methylphenacyl acetate, m.p. 85°-85° C.

Sources & evidence

ORD record: ord-9883ff7a2a49447fbb2b8e936feb39bd
Source dataset: uspto-grants-1977_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04054719

Reaction notes

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