HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 7-bromoheptanoate → Methyl 5-oxocyclopent-1-ene-1-heptanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 7-bromoheptanoate | HCID 554086 | — |
| Reactant | Methyl 6-Bromohexanoate | HCID 4170292 | — |
| Reactant | Methyl 8-bromooctanoate | HCID 11107373 | — |
| Reactant | Methyl 7-bromohept-5-ynoate | HCID 11287432 | — |
| Reactant | Methyl 6-bromo-4-hexenoate | HCID 53917093 | — |
| Reactant | Methyl 6-(5-oxocyclopent-1-en-1-yl)hex-4-enoate | HCID 54282459 | — |
| Reactant | 8-(5-Oxocyclopent-1-enyl)-6-octenoic acid methyl ester | HCID 54454534 | — |
| Reactant | Methyl 8-bromo-6-octenoate | HCID 54475740 | — |
| Reactant | Methyl 7-(5-oxocyclopent-1-en-1-yl)hept-5-enoate | HCID 54504603 | — |
| Product | Methyl 5-oxocyclopent-1-ene-1-heptanoate | HCID 2777884 | — |
| Product | Methyl 8-(5-oxocyclopent-1-EN-1-YL)octanoate | HCID 14543894 | — |
| Product | Methyl 6-(5-oxo-1-cyclopenten-1-yl)hexanoate | HCID 21420525 | — |
Reaction Steps
Alternatively 6-(5-oxocyclopent-1-enyl)-4-hexenoic acid methyl ester, 7-(5-oxocyclopent-1-enyl)-5-heptenoic acid methyl ester and 8-(5-oxocyclopent-1-enyl)-6-octenoic acid methyl ester, as well as, 6-(5-oxocyclopent-1enyl)hexanoic acid methyl ester, 7-(5-oxocyclopent-1-enyl)heptanoic acid methyl ester, and 8-(5-oxocyclopent-1-enyl)octanoic methyl ester are prepared by following serially the procedures of Examples 13, 14 and 15, and using methyl 6-bromo-4-hexenoate, methyl 7-bromo-5-heptanoate, methyl 8-bromo-6-octenoate, methyl 6-bromohexanoate, methyl 7-bromoheptanoate, and methyl 8-bromooctanoate, respectively, as starting material instead of methyl 7-bromo-5-heptynoate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04054741 |
| Source dataset | uspto-grants-1977_10 |
| ORD ID | ord-a973a92b0677429bb16dfecd0911b9ba |
| Source note | uspto-grants-1977_10 |