HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 54290981, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Sec-Butylamine | HCID 24874 | — |
| Reactant | 6-Chloro-N-ethyl-5-nitro-2-(trifluoromethyl)pyrimidin-4-amine | HCID 21400891 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 54290981 | HCID 54290981 | 73.2% |
Reaction Steps
5.4 g (0.02 mol) of 4-ethylamino-6-chloro-5-nitro-2-trifluoromethyl-pyrimidine are dissolved in 100 ml of abs. ethanol. The solution is treated with 2.3 g of triethylamine (0.023 mol) and 1.7 g (0.023 mol) of 2-amino-butane and the mixture is stirred overnight. After the mixture has been evaporated, the product is taken up in water and extracted with ether to yield 4.5 g of 4-ethylamino-5-nitro-6-(2-butylamino)-2-trifluoromethyl-pyrimidine; nD20 = 1.5209.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04055411 |
| Source dataset | uspto-grants-1977_10 |
| ORD ID | ord-dec34ef8612d4ceba4b735b502623fc4 |
| Source note | uspto-grants-1977_10 |