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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 973135Generated: October 25, 2026

1,4-Bis(3-aminopropyl)piperazine → (3-Chloropropanoyl)urea

https://huagongshe.com/reaction/973135

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-Bis(3-aminopropyl)piperazineHCID 81629—
Reactant3-Chloropropanoyl isocyanateHCID 13572374—
Product(3-Chloropropanoyl)ureaHCID 12937417318.8%

Reaction Steps

In the same way as in Example 1, reaction of 10.0 g (50 mmols) of N,N'-bis(3-aminopropyl)piperazine with 14.3 g (106 mmols) of 3-chloropropionyl isocyanate gives 24.0 g of the 3-chloropropionylurea compound of the formula ##STR11##

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04055431
Source datasetuspto-grants-1977_10
ORD IDord-b96a6483b0914c7fbe56c2cf803e7456
Source noteuspto-grants-1977_10