p-Cyclohexyl-alpha-methylbenzylamine hydrochloride → 2-(rho-Cyclohexyl-alpha-methylbenzylimino)hexahydroazepine hydrochloride

HRID 973170Notes

Reaction equation

HRID 973170 reaction equation
[ClH:1].[CH:2]1([C:8]2[CH:16]=[CH:15][C:11]([CH:12]([NH2:14])[CH3:13])=[CH:10][CH:9]=2)[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]1.Cl.C[CH:19]([NH2:34])[C:20]1C=[CH:24][C:23](CCC2C=CC=CC=2)=[CH:22][CH:21]=1>>[ClH:1].[CH:2]1([C:8]2[CH:9]=[CH:10][C:11]([CH:12]([N:14]=[C:19]3[CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][NH:34]3)[CH3:13])=[CH:15][CH:16]=2)[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7]1

Participants

3

Reactant 2

HCID 13012105p-Cyclohexyl-alpha-methylbenzylamine hydrochlorideHCID 13012107alpha-Methyl-p-phenethylbenzylamine hydrochloride

Product 1

HCID 1784632892-(rho-Cyclohexyl-alpha-methylbenzylimino)hexahydroazepine hydrochloride

Procedure

Following essentially the same procedure described in Example IV above and substituting ρ-cyclohexyl-α-methylbenzylamine hydrochloride for the α-methyl-ρ-phenyethylbenzylamine hydrochloride above, results in the formation of 2-(ρ-cyclohexyl-α-methylbenzylimino)hexahydroazepine hydrochloride having a M.P. of 245°-7° C.

Sources & evidence

ORD record
ord-f765477b29c84d9bbbdc6becef562af2
Source dataset
uspto-grants-1977_10
Patent number
US04055561

Reaction notes

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