HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Hexanol → Hexyl 2-hydroxy-2-methylpropanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Hexanol | HCID 8103 | — |
| Reactant | Propanamide, 2-hydroxy-2-methyl- | HCID 83059 | — |
| Product | Hexyl 2-hydroxy-2-methylpropanoate | HCID 21401559 | 51.8% |
Reaction Steps
A mixture of 20.6 g of α-hydroxy-isobutyramide and 204 g of n-hexyl alcohol was heated in the presence of 0.45 g of PbO for 6 hours at 200° C. in an autoclave. On working up by distillation, 19.5 g (= 51.8 percent of theory) of α-hydroxy-isobutyric acid-n-hexyl-ester were obtained. The amide conversion is 75 percent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04055590 |
| Source dataset | uspto-grants-1977_10 |
| ORD ID | ord-cd14d858d59547409c78185637444a00 |
| Source note | uspto-grants-1977_10 |