Sodium Hydroxide → 8-Carbamoyl-12-hydroxyheptadecanoic acid

HRID 973346Notes

Reaction equation

HRID 973346 reaction equation
[C:1]([CH:4]([CH2:16][CH2:17][CH2:18][CH:19]([O:25]C(=O)C)[CH2:20][CH2:21][CH2:22][CH2:23][CH3:24])[CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][C:11]([O:13]CC)=[O:12])(=[O:3])[NH2:2].[OH-].[Na+]>O.CO>[C:1]([CH:4]([CH2:16][CH2:17][CH2:18][CH:19]([OH:25])[CH2:20][CH2:21][CH2:22][CH2:23][CH3:24])[CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][C:11]([OH:13])=[O:12])(=[O:3])[NH2:2]

Participants

5

Reactant 2

HCID 14798Sodium HydroxideHCID 21401682HCID 21401682, compound

Product 1

HCID 214017178-Carbamoyl-12-hydroxyheptadecanoic acid

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 962WaterSolvent

Procedure

Ethyl 8-carbamoyl-12-acetoxyheptadecanoate (5.50 g., 0.0138 mole) is added to a solution of sodium hydroxide (1.66 g., 0.0414 mole) in water (8 ml.) and methanol (72 ml.). The resulting solution is allowed to stand 24 hours at 25° C.

Sources & evidence

ORD record
ord-731ed19e12fd4b8d8d88e0c0a155fbba
Source dataset
uspto-grants-1977_10
Patent number
US04055597

Reaction notes

Loading…