反应详情

A nitrating acid prepared at -10° C. by adding 55 ml of concentrated H2SO4 to 20 ml of 98 percent HNO3 was added dropwise, in the course of 60 minutes, to a solution of 63.4 g (0.34 mole) of 2-bromobenzaldehyde in 110 ml of concentrated H2SO4 at -5° C. Stirring was continued for a further 45 minutes, after which the reaction mixture was poured onto 550 g of ice, and the precipitated solid was filtered off under suction, washed with water, then with 10 percent strength Na2CO3 solution and again with water. Drying under reduced pressure at 50° C. gave 72 g (92% of theory) of product as a yellow solid of melting point 86°-88° C.

1. customA nitrating acid prepared at -10° C.
2. filtrationthe precipitated solid was filtered off under suction
3. washwashed with water
4. customDrying under reduced pressure at 50° C.
5. customgave 72 g (92% of theory) of product as a yellow solid of melting point 86°-88° C.