2,6-Diisopropylphenyl isocyanate → HCID 15020212, compound

HRID 973450Notes

Reaction equation

HRID 973450 reaction equation
[CH2:1]([C:7]1[CH:13]=[CH:12][CH:11]=[CH:10][C:8]=1[NH2:9])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].[CH:14]([C:17]1[CH:22]=[CH:21][CH:20]=[C:19]([CH:23]([CH3:25])[CH3:24])[C:18]=1[N:26]=[C:27]=[O:28])([CH3:16])[CH3:15]>CCCCCC>[CH2:1]([C:7]1[CH:13]=[CH:12][CH:11]=[CH:10][C:8]=1[NH:9][C:27]([NH:26][C:18]1[C:17]([CH:14]([CH3:15])[CH3:16])=[CH:22][CH:21]=[CH:20][C:19]=1[CH:23]([CH3:25])[CH3:24])=[O:28])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6]

Participants

4

Reactant 2

HCID 922592,6-Diisopropylphenyl isocyanateHCID 571833HCID 571833, compound

Product 1

HCID 15020212HCID 15020212, compoundYield 61%

Reagents, catalysts & solvents 1

HCID 8058HexaneSolvent2×

Procedure

To a 5 ml n-hexane solution of 0.42 g (2.35 mmol) of 2-hexylaniline was added 5 ml (2.35 mmol) of a hexane solution of 0.47M 2,6-diisopropylphenyl isocyanate at room temperature and the whole was stirred for 16 hours. The precipitated crystals were collected by filtration to give 0.55 g (61% yield) of 1-(2-hexylphenyl)-3-(2,6-diisopropylphenyl)urea, the physical properties of which being shown in the following Table 3. The compound No. 25 listed in Table 3 was similarly prepared as above.

Workup

  1. filtrationThe precipitated crystals were collected by filtration

Sources & evidence

ORD record
ord-7d020884b20b427f96d3b696b8acad95
Source dataset
uspto-grants-1991_11
Patent number
US05063247

Reaction notes

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