HCID 14213078, compound → (R)-2-Benzyl-succinic acid 1-benzyl ester

Participants

Reaction Steps

The product from Example 22 (0.52 g, 1.47 mmol) was dissolved in a 1:1 (v:v) solution (6 ml) of trifluoroacetic acid and dichloromethane and stirred at room temperature for 1 h. The volatiles were removed in vacuo to provide the title compound (0.437 g, 100%) as an oil which crystallized on standing. The unpurified material was of sufficient purity to employ in subsequent steps. Mass spectrum: (M)+ =298.

Provenance & Evidence