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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 973551Generated: October 30, 2026

Dimethylformamide → 4-Cyano-2-(3-cyanophenyl)-pyridine

https://huagongshe.com/reaction/973551

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
Reactant4-Chloro-2-(3-bromophenyl)-pyridineHCID 19988650—
ReactantHCID 178418260HCID 178418260—
Product4-Cyano-2-(3-cyanophenyl)-pyridineHCID 19988656—

Reaction Steps

Starting from 4-chloro-2-(3-bromophenyl)-pyridine, the title compound is prepared by reaction with copper cyanide in boiling N,N-dimethylformamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05064832
Source datasetuspto-grants-1991_11
ORD IDord-58500937992f497fbdcd8217a91d8ebb
Source noteuspto-grants-1991_11