HCID 178503534, compound → HCID 178509694, compound

HRID 973553Notes

Reaction equation

HRID 973553 reaction equation
[C:1]([C:3]1[CH:4]=[C:5]([C:9]2[N:14]=[C:13](SC)[N:12]=[C:11]([OH:17])[CH:10]=2)[CH:6]=[CH:7][CH:8]=1)#[N:2]>[Ni]>[C:1]([C:3]1[CH:4]=[C:5]([C:9]2[N:14]=[CH:13][N:12]=[C:11]([OH:17])[CH:10]=2)[CH:6]=[CH:7][CH:8]=1)#[N:2]

Participants

3

Reactant 1

HCID 178503534HCID 178503534, compound

Product 1

HCID 178509694HCID 178509694, compound

Reagents, catalysts & solvents 1

HCID 935NickelCatalyst

Procedure

Starting from 6-(3-cyanophenyl)-4-hydroxy-2-methylthiopyrimidine [=4-(3-cyanophenyl)-6-hydroxy-2-methylthiopyrimidine, see Example 10a], the title compound is obtained by desulfurisation with Raney nickel in boiling ethanol.

Sources & evidence

ORD record
ord-a48198a50c504a3bbbdd973ab858f99a
Source dataset
uspto-grants-1991_11
Patent number
US05064832

Reaction notes

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