HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Methylaniline → HCID 10339142, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Methylaniline | HCID 7515 | — |
| Reactant | 2,4-Dichloro-8-methoxyquinazoline | HCID 10421331 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 10339142 | HCID 10339142 | 15% |
Reaction Steps
8-Methoxy-2,4-dichloroquinazoline (1.5 g, 0.007 mol) was heated under reflux in a solution of N-methyl aniline (1.43 m), 0.014 mol) in tetrahydrofuran (50 ml) for 16 hours precipitating a solid, which was collected and crystallised from ethanol/water to give 2,4-bis-(N-methylphenylamino)-8-methoxyquinazoline (0.37 g, 15%), m.p. 169°-170°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05064833 |
| Source dataset | uspto-grants-1991_11 |
| ORD ID | ord-f9e03fea41354a70a20ceef0cb3b36e0 |
| Source note | uspto-grants-1991_11 |