HuagongsheHuagongshe Chemistry Print Report · For research reference only
O-Toluidine → 4(1H)-Quinazolinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | O-Toluidine | HCID 7242 | — |
| Reactant | 2-(Methylsulfanyl)quinazolin-4(1H)-one | HCID 135427104 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4(1H)-Quinazolinone | HCID 135408753 | 140.8% |
Reaction Steps
2-Methylthio-4-quinazolone (10.0 g, 0.052 mol) was fused with o-toluidine (8.35 g, 0.078 mol) at 160°. After 4 hours, the solid was treated with ethanol, and filtered to give 2-methylphenylamino)-4-quinazolone (10.7 g, 82%) m.p. 278°-280°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05064833 |
| Source dataset | uspto-grants-1991_11 |
| ORD ID | ord-0ed04304e00b428f86a81cd99908a783 |
| Source note | uspto-grants-1991_11 |