HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 10036464, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | HCID 10420903 | HCID 10420903 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 10036464 | HCID 10036464 | — |
Reaction Steps
A mixture of 11.0 g of isopropyl 2-cyanoethyl(t-butyl)phosphinate, 17.0 g of ammonia and 1.7 g of Raney-Nickel in 110 ml of ethanol is hydrogenated during 5 hours. The catalyst is filtered off and the solvent removed by evaporation. The crude oil is purified by Kugelrohr-distillation to yield isopropyl 3-aminopropyl(t-butyl)phosphinate as an oil, b.p. 155°/1 Pa, nD20 =1.4600.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05064819 |
| Source dataset | uspto-grants-1991_11 |
| ORD ID | ord-874720c2b4c049e282b63f024620b13c |
| Source note | uspto-grants-1991_11 |