HuagongsheHuagongshe Chemistry Print Report · For research reference only
1H-1,2,4-Triazole → HCID 86745200, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1H-1,2,4-Triazole | HCID 9257 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Reactant | HCID 19021627 | HCID 19021627 | — |
| Reactant | Dichloromethane methanol | HCID 21226129 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 86745200 | HCID 86745200 | — |
Reaction Steps
React 1-benzyl-3-chloromethyl-2(1H)-quinolone with the sodium salt of 1,2,4-triazole in DMF at 25° C. for 18 hours, following the procedure of example 22. Chromatograph the crude product using 5% methanol-dichloromethane to obtain the major product, 1-Benzyl-3-(1H-1,2,4-triazol-1-ylmethyl-2(1H)-Quinolone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05064837 |
| Source dataset | uspto-grants-1991_11 |
| ORD ID | ord-c17aa02fef9347d69e3f2c9c41f7553c |
| Source note | uspto-grants-1991_11 |