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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 973654Generated: October 31, 2026

Dimethylformamide → (1-3-Chlorophenyl)-3-(1H-1,2,4-Triazol-1-ylmethyl)-2(1H)-Quinolone

https://huagongshe.com/reaction/973654

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
Reactant1-(3-chlorophenyl)-3-chloromethyl-2(1H)-quinoloneHCID 19021644—
ReactantHCID 178507080HCID 178507080—
Product(1-3-Chlorophenyl)-3-(1H-1,2,4-Triazol-1-ylmethyl)-2(1H)-QuinoloneHCID 19021633—

Reaction Steps

Following the procedure of example 22, react 1-(3-chlorophenyl)-3-chloromethyl-2(1H)-quinolone with sodium triazole in dimethylformamide. Chromatograph to obtain the major product, 1-(3-Chlorophenyl)-3-(1H-1,2,4-Triazol-1-ylmethyl)-2(1H)-Quinolone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05064837
Source datasetuspto-grants-1991_11
ORD IDord-58f3621c84c346d38be49759df5b8108
Source noteuspto-grants-1991_11