Water → 2-(2,6-dichloro-4-trifluoromethylphenyl)-2H-1,2,3-triazole-4-carboxylic acid

HRID 973686Notes

Reaction equation

HRID 973686 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:5]=[C:4]([Cl:12])[C:3]=1[N:13]1[N:17]=[C:16]([CH:18]=[O:19])[CH:15]=[N:14]1.[OH2:20]>S(=O)(=O)(O)O.[O-2].[O-2].[O-2].[Cr+6]>[Cl:12][C:4]1[CH:5]=[C:6]([C:8]([F:11])([F:9])[F:10])[CH:7]=[C:2]([Cl:1])[C:3]=1[N:13]1[N:17]=[C:16]([C:18]([OH:20])=[O:19])[CH:15]=[N:14]1

Participants

5

Reactant 2

HCID 962WaterHCID 197783082-(2,6-Dichloro-4-trifluoromethylphenyl)-1,2,3-triazole-4-carboxaldehyde

Product 1

HCID 541736102-(2,6-dichloro-4-trifluoromethylphenyl)-2H-1,2,3-triazole-4-carboxylic acid

Reagents, catalysts & solvents 2

HCID 10219390chromium (VI) trioxideCatalystHCID 1118Sulfuric AcidSolvent

Procedure

2-(2,6-dichloro-4-trifluoromethylphenyl)-2H-1,2,3-triazole-4-carboxaldehyde (1 g) was oxidised using chromium trioxide (26.67 g) in water (40 ml) and concentrated sulphuric acid (23 ml), made up to 100 ml. The product was extracted with ether and worked up in conventional manner to give 2-(2,6-dichloro-4-trifluoromethylphenyl)-2H-1,2,3-triazole-4-carboxylic acid, m.p. 155°-157°.

Workup

  1. extractionThe product was extracted with ether

Sources & evidence

ORD record
ord-f3615841c3614c63a8851a9a5172e9cc
Source dataset
uspto-grants-1991_11
Patent number
US05064844

Reaction notes

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