1-Naphthaleneacetic Acid → 2-(Naphthalen-1-yl)acetyl chloride

Participants

Reaction Steps

15 g of 1-naphthyl acetic acid and 90 ml of thionyl chloride were heated with stirring for 2 hours and the solution was concentrated under reduced pressure. The residue was taken up in toluene and concentrated to dryness under reduced pressure to obtain 16.3 g of the expected product which used as is for the next step.

Provenance & Evidence