Sodium Dithionite → HCID 178508113, compound

HRID 973772Notes

Reaction equation

HRID 973772 reaction equation
[C:1]1([C:10](=[O:11])[NH:9][C:7](=[O:8])[NH:6][C:4]1=[O:5])=[N:2]O.S(S([O-])=O)([O-])=O.[Na+].[Na+]>O>[NH2:2][C:1]1[C:4]([OH:5])=[N:6][C:7]([OH:8])=[N:9][C:10]=1[OH:11]

Participants

4

Reactant 2

HCID 24489Sodium DithioniteHCID 178518525HCID 178518525, compound

Product 1

HCID 178508113HCID 178508113, compoundYield 82.3%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
70 °C

Procedure

100 g of violuric acid was added to 1 liter of water with vigorous overhead stirring and heated to 70° C. 200 g sodium hydrosulfite was added in portions over 15 minutes. After 2.5 hours the reaction was filtered and the precipitate rinsed with water. The solid was dried under vacuum at 98° C. for 3 hours to yield 75 g of 5-amino-2,4,6-trihydroxypyrimidine.

Workup

  1. filtrationAfter 2.5 hours the reaction was filtered
  2. washthe precipitate rinsed with water
  3. customThe solid was dried under vacuum at 98° C. for 3 hours

Sources & evidence

ORD record
ord-969cd144f7b345f3a9ce4c5d621cb55b
Source dataset
uspto-grants-1991_11
Patent number
US05064947

Reaction notes

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