4-(1-Bromoethyl)-1,2-difluorobenzene → tert-butyl N-[[4-[1-(3,4-difluorophenyl)ethyl]morpholin-2-yl]methyl]carbamate
Reaction equation
[Br:26][CH:27]([CH3:28])[c:29]1[cH:30][c:31]([F:36])[c:32]([F:35])[cH:33][cH:34]1.[Cl:1][c:2]1[cH:3][c:4]([CH:5]([CH3:6])[N:11]2[CH2:12][CH:13]([CH2:17][NH:18][C:19]([O:20][C:21]([CH3:22])([CH3:23])[CH3:24])=[O:25])[O:14][CH2:15][CH2:16]2)[cH:7][cH:8][c:9]1[Cl:10]>>[N:11]1([CH:27]([CH3:28])[c:29]2[cH:30][c:31]([F:36])[c:32]([F:35])[cH:33][cH:34]2)[CH2:12][CH:13]([CH2:17][NH:18][C:19]([O:20][C:21]([CH3:22])([CH3:23])[CH3:24])=[O:25])[O:14][CH2:15][CH2:16]1Participants
3
Sources & evidence
- ORD record
- ord-af35930c8440496fa3a80553cc85ec7e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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