HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylmalonic Acid → 3-(Dimethylamino)-2-methylpropanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylmalonic Acid | HCID 487 | — |
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | Formaldehyde | HCID 712 | — |
| Solvent | Water | HCID 962 | — |
| Product | 3-(Dimethylamino)-2-methylpropanoic acid | HCID 14073324 | — |
Reaction Conditions
| Temperature | 0 °C |
|---|
Reaction Steps
In 1.0 ml of water was dissolved 1.5 g of methylmalonic acid, after which 1.26 g of a 50% aqueous dimethylamine solution and 0.96 ml of a 37% aqueous formaldehyde solution were added with stirring at 0° C., and the resulting mixture was stirred at 0° to 5° C. for 3 hours and then at 80° C. for 30 minutes.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05064945 |
| Source dataset | uspto-grants-1991_11 |
| ORD ID | ord-cc3d7a87fd854185b231c67ec2bf855a |
| Source note | uspto-grants-1991_11 |