HCID 54096413, compound → HCID 54287611, compound

HRID 973794Notes

Reaction equation

[N:1]([C@@H:4]1[C@@H:8]([CH:9]([S:11]([CH3:14])(=[O:13])=[O:12])[OH:10])[O:7][C@@H:6]([N:15]2[CH:23]=[C:21]([CH3:22])[C:19](=[O:20])[NH:18][C:16]2=[O:17])[CH2:5]1)=[N+:2]=[N-:3].C(C(O)[C@H]1O[C@@H](N2C=C(C)C(=O)N([C:42](=[O:49])[C:43]3[CH:48]=[CH:47][CH:46]=[CH:45][CH:44]=3)C2=O)C[C@@H]1N=[N+]=[N-])(=O)C.C(C(O)[C@H]1O[C@@H](N2C=C(C)C(=O)NC2=O)C[C@@H]1N=[N+]=[N-])(=O)C>>[N:1]([C@@H:4]1[C@@H:8]([CH:9]([S:11]([CH3:14])(=[O:12])=[O:13])[OH:10])[O:7][C@@H:6]([N:15]2[CH:23]=[C:21]([CH3:22])[C:19](=[O:20])[N:18]([C:42](=[O:49])[C:43]3[CH:48]=[CH:47][CH:46]=[CH:45][CH:44]=3)[C:16]2=[O:17])[CH2:5]1)=[N+:2]=[N-:3]

Participants

Reactant 3

HCID 54096413HCID 54096413, compound

HCID 86745211HCID 86745211, compound

HCID 86745212HCID 86745212, compound

Product 1

HCID 54287611HCID 54287611, compound

Procedure

3'-Azido-3-benzoyl-3'-deoxy-5'-mesylthymidine was prepared from 3'-azido-3'-deoxy-5'-mesylthymidine by an analogous method to that used in Example 40 to prepare 5'-acetyl-3'-azido-3-benzoyl-3'-deoxythymidine from 5'-acetyl-3'-azido-3'-deoxythymidine; m.p.=86°-88° C.

Sources & evidence

ORD record: ord-f8532acc8743497785e1f51882e2c1c4
Source dataset: uspto-grants-1991_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05064946

Reaction notes

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