Formic Acid → HCID 178507217, compound

HRID 973855Notes

Reaction equation

HRID 973855 reaction equation
[NH2:1][N:2]1[C:7]([NH2:8])=[CH:6][C:5]([NH2:9])=[N:4][C:3]1=[S:10].[CH:11](O)=O>>[NH2:9][C:5]1[N:4]=[C:3]([SH:10])[N:2]2[N:1]=[CH:11][N:8]=[C:7]2[CH:6]=1

Participants

3

Reactant 2

HCID 284Formic AcidHCID 14918341,4,6-Triaminopyrimidine-2-thione

Product 1

HCID 178507217HCID 178507217, compound

Procedure

A mixture of 1,4,6-triamino-2(1H)-pyrimidinethione (2.0 g) and 40 ml of formic acid was refluxed for seven hours. After concentrating under reduced pressure, 80 ml of water was added to the residue, the mixture was refluxed for one hour, and the crystals formed upon cooling were collected by filtration and washed with methanol, giving 1.6 g of the objective compound as faint yellow crystals.

Workup

  1. temperaturewas refluxed for seven hours
  2. concentrationAfter concentrating under reduced pressure, 80 ml of water
  3. additionwas added to the residue
  4. temperaturethe mixture was refluxed for one hour
  5. customthe crystals formed
  6. temperatureupon cooling
  7. filtrationwere collected by filtration
  8. washwashed with methanol

Sources & evidence

ORD record
ord-083cf267440c4a7e9a1fc73fba0ef89d
Source dataset
uspto-grants-1991_11
Patent number
US05064953

Reaction notes

Loading…