HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosgene → HCID 15675496, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosgene | HCID 6371 | — |
| Reactant | Methylhydroxylamine | HCID 11647 | — |
| Reactant | Isocyanate | HCID 105034 | — |
| Reactant | HCID 19987249 | HCID 19987249 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 15675496 | HCID 15675496 | — |
Reaction Steps
By the method of Example 32 above, 7-(benzyloxy)heptylamine hydrochloride was converted to the isocyanate by treatment with phosgene in toluene, and then treated with N-methylhydroxylamine. Chromatography on silica gel, and recrystallization from ethyl acetate-hexane, provided the title compound as a white solid, mp 69°-70.5° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05066658 |
| Source dataset | uspto-grants-1991_11 |
| ORD ID | ord-47a9119d0381448eb0a23452aef9ea50 |
| Source note | uspto-grants-1991_11 |