N-[[5-(1,1-difluoroethyl)-2-(trifluoromethoxy)phenyl]methyl]-2-phenylpiperidin-3-amine → HCID 10272722, compound

HRID 97404Notes

Reaction equation

HRID 97404 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH:9]([c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[CH:10]([NH:14][CH2:15][c:16]2[c:17]([O:29][CH3:30])[cH:18][cH:19][c:20]([C:22]([C:23]([F:24])([F:25])[F:26])([CH3:27])[CH3:28])[cH:21]2)[CH2:11][CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[F:37][C:38]([c:39]1[cH:40][cH:41][c:42]([O:43][C:44]([F:45])([F:46])[F:47])[c:48]([CH2:50][NH:51][CH:52]2[CH2:53][CH2:54][CH2:55][NH:56][CH:57]2[c:58]2[cH:59][cH:60][cH:61][cH:62][cH:63]2)[cH:49]1)([F:64])[CH3:65]>>[NH:8]1[CH:9]([c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[CH:10]([NH:14][CH2:15][c:16]2[c:17]([O:29][CH3:30])[cH:18][cH:19][c:20]([C:22]([C:23]([F:24])([F:25])[F:26])([CH3:27])[CH3:28])[cH:21]2)[CH2:11][CH2:12][CH2:13]1

Participants

3

Reactant 2

HCID 18677617N-[[5-(1,1-difluoroethyl)-2-(trifluoromethoxy)phenyl]methyl]-2-phenylpiperidin-3-amineHCID 18677634Tert-butyl 3-[[2-methoxy-5-(1,1,1-trifluoro-2-methylpropan-2-yl)phenyl]methylamino]-2-phenylpiperidine-1-carboxylate

Product 1

HCID 10272722HCID 10272722, compound

Sources & evidence

ORD record
ord-d530df7420834df680271ef3538874de
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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