2-Pyridinecarbonitrile, 4-methoxy-3,5-dimethyl- → 3,5-Dimethyl-2-hydroxymethyl-4-methoxy-pyridine

Participants

Reaction Steps

The invention accordingly relates to a process for the preparation of compounds of formula I ##STR2## in which X is the radical OH or Cl , comprising catalytical hydrogenation of 3,5-dimethyl-4-methoxy-2-cyanopyridine of formula II in the presence of an inert diluent, the resulting 3,5-dimethyl-4-methoxy-2-aminomethylpyridine of formula III ##STR3## being then reacted with sodium nitrite in aqueous-acidic solution to give 3,5-dimethyl-4-methoxy-2-hydroxymethylpyridine and, if desired, the latter being then reacted with thionyl chloride to give 3,5-dimethyl-4-methoxy-2-chlormethylpyridine.

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