HuagongsheHuagongshe Chemistry Print Report · For research reference only
Toluene → Isoprocarb
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | Carbamic acid, N-methyl-, ethyl ester | HCID 7752 | — |
| Reactant | 2-Isopropoxyphenol | HCID 20949 | — |
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Product | Isoprocarb | HCID 17517 | — |
Reaction Steps
To a solution of 2-isopropoxyphenol (1.38 g, 0.01 mole) and ethyl N-methylcarbamate (1.03 g, 0.01 mole) in toluene (10 ml), was added phosphoryl chloride (1.54 g, 0.01 mole) and refluxed for six hours. The reaction mixture was worked up as described earlier to give 2-isopropylphenyl N-methylcarbamate of the formula (VII) as a solid, crystallised from pet. ether, m.p. 88° C. to 93° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05066819 |
| Source dataset | uspto-grants-1991_11 |
| ORD ID | ord-1c2836f87b1c471cb665418b0a825c75 |
| Source note | uspto-grants-1991_11 |