HuagongsheHuagongshe Chemistry Print Report · For research reference only
4'-Methoxyacetophenone → HCID 15030131, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4'-Methoxyacetophenone | HCID 7476 | — |
| Reactant | Methyl formate | HCID 7865 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | HCID 15169762 | HCID 15169762 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 15030131 | HCID 15030131 | — |
Reaction Steps
3-(4-morpholinylmethyl)-6-(4-methoxvbenzoyl)-2,3-dihydropyrrolo[1,2,3-de]-1,4-benzoxazine, m.p. 209°-214° C. (1.5 g from ethyl acetate) was prepared by reaction of 13 g (0.052 mole) of 3-(4-morpholinylmethyl)-4-amino-3,4-dihydro-2H-1,4-benzoxazine with 10.2 g (0.057 mole) 8-(4-methoxyphenyl)-8-ketopropionaldehyde in glacial acetic acid (the 8-ketopropionaldehyde being prepared by reaction of 4-methoxyacetophenone with methyl formate in diethyl ether in the presence of ethanol and sodium hydride).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05066803 |
| Source dataset | uspto-grants-1991_11 |
| ORD ID | ord-3bea88a217d5427dad2026850adc900f |
| Source note | uspto-grants-1991_11 |