HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Toluenesulfonic acid → 1-(4-Methoxyphenyl)-2-[4-(4-pentylcyclohexen-1-yl)-phenyl]-acetylene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | 4-Pentylcyclohexanone | HCID 566097 | — |
| Reactant | 4-[(4-bromophenyl) ethynyl] phenyl methyl ether | HCID 11709015 | — |
| Reactant | 4-Methoxy-4'-(1-hydroxy-4-pentylcyclohexyl)-tolan | HCID 67944121 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 1-(4-Methoxyphenyl)-2-[4-(4-pentylcyclohexen-1-yl)-phenyl]-acetylene | HCID 19983831 | — |
Reaction Steps
0.2 mol of 4-methoxy-4'-(1-hydroxy-4-pentylcyclohexyl)-tolan (prepared by reaction of a Grignard compound of 4-bromo-4'-methoxytolan with 4-pentylcyclohexanone) is heated in 400 ml of toluene and with 1 g of p-toluenesulfonic acid for 1 hour using a water separator. The reaction mixture is washed, dried and evaporated. Customary working up gives 1-(4-methoxyphenyl)-2-[4-(4-pentylcyclohexen-1-yl)-phenyl]-acetylene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05068053 |
| Source dataset | uspto-grants-1991_11 |
| ORD ID | ord-e18e44fb9030425ab55c9db7b212f32e |
| Source note | uspto-grants-1991_11 |