HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene, 1-bromo-4-(trifluoromethyl)- → HCID 178444406, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene, 1-bromo-4-(trifluoromethyl)- | HCID 67872 | — |
| Reactant | HCID 178455744 | HCID 178455744 | — |
| Catalyst | Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI) | HCID 24350 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 178444406 | HCID 178444406 | — |
Reaction Steps
A mixture of 0.06 mol of trans-4-pentylcyclohexylacetylene, 0.06 mol of 4-trifluoromethyl-bromobenzene, 250 ml of triethylamine, 1.2 mmol of Pd(II) catalyst and 0.6 mmol of CuI is stirred at room temperature for 15 hours. The reaction mixture is diluted with petroleum ether and filtered. Evaporation and purification give 1-(trans-4-pentylcyclohexyl)-2-(4-trifluoromethylphenyl)acetylene of M.=43°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05068053 |
| Source dataset | uspto-grants-1991_11 |
| ORD ID | ord-a7ae0d83fe734c668005c4a7a79eb028 |
| Source note | uspto-grants-1991_11 |