反应详情

Using the procedure of Step C of Example 1, 2.3 g of 1-naphthylacetic acid and 2 g of the product of Step B of Example 1 were reacted to obtain 5.3 g of crude product which was purified by chromatography on silica (methylene chloride 9-methanol 1). After crystallization from ethyl ether, 1.9 g of product melting at 117° C. were obtained which was crystallized from isopropyl ether to obtain 1.1 g of the expected product melting at 125° C.

1. customwere reacted
2. customto obtain 5.3 g of crude product which
3. customwas purified by chromatography on silica (methylene chloride 9-methanol 1)
4. customAfter crystallization from ethyl ether