HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-tert-Butylcyclohexanone → HCID 14406817, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-tert-Butylcyclohexanone | HCID 7392 | — |
| Reactant | Sodium cyanoborohydride | HCID 5003444 | — |
| Reactant | 3-[4-(1,1-Dimethylethyl)phenyl]pyrrolidine | HCID 14406816 | — |
| Catalyst | Zincchloride | HCID 3007855 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 14406817 | HCID 14406817 | — |
Reaction Steps
15.4 g (100 millimoles) of 4-tert-butylcyclohexanone, 9.8 g (48 millimoles) of 3-(4-tert-butylphenyl)-pyrrolidine, 6.8 g (50 millimoles) of zinc(II) chloride and 6.3 g (100 millimoles) of sodium cyanoborohydride in 200 ml of absolute methanol were stirred for 48 hours at 22° C. The methanol was distilled off under reduced pressure and the residue was dissolved in dichloromethane and 5% strength sodium hydroxide solution.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05068245 |
| Source dataset | uspto-grants-1991_11 |
| ORD ID | ord-b6c1614e8ca847e8ba6d23843b2b98c1 |
| Source note | uspto-grants-1991_11 |