HuagongsheHuagongshe Chemistry Print Report · For research reference only
m-Chloroperbenzoic acid → (+-)-p-(3-(Ethyl(3-(propylsulfinyl)propyl)amino)-2-hydroxypropoxy)benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | m-Chloroperbenzoic acid | HCID 70297 | — |
| Reactant | 4-[3-[ethyl[3-(propylthio)propyl]amino]-2(R)-hydroxypropoxy]benzonitrile | HCID 15066844 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | (+-)-p-(3-(Ethyl(3-(propylsulfinyl)propyl)amino)-2-hydroxypropoxy)benzonitrile | HCID 15066846 | — |
Reaction Steps
Oxidation of 4-[3-[ethyl[3-(propylthio)propyl]amino]-2(R)-hydroxypropoxy]benzonitrile with m-chloroperbenzoic acid was carried out as described for the stereoisomeric mixture in example 3. [α]D20 -18.6° (C 1.0, CH3OH).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05068272 |
| Source dataset | uspto-grants-1991_11 |
| ORD ID | ord-0cbb66ddd3ee49ae9efb25127005fbe4 |
| Source note | uspto-grants-1991_11 |