Ethylamine → HCID 15924276, compound

HRID 974252Notes

Reaction equation

HRID 974252 reaction equation
[C:1]([CH2:6][CH2:7][CH:8]1[C:13](=O)[CH2:12][CH2:11][CH2:10][C:9]1=[O:15])([O:3]CC)=O.[CH2:16]([NH2:18])[CH3:17]>>[CH2:16]([N:18]1[C:13]2[CH2:12][CH2:11][CH2:10][C:9](=[O:15])[C:8]=2[CH2:7][CH2:6][C:1]1=[O:3])[CH3:17]

Participants

3

Reactant 2

HCID 6341EthylamineHCID 11745931HCID 11745931, compound

Product 1

HCID 15924276HCID 15924276, compound

Procedure

21.2 g (0.1 mol) of 2-(2-carbethoxy-ethyl)-cyclohexan- 1,3-dione and 200 ml of 24% ethanolic ethylamine solution are heated to 180° C. in a stirred autoclave for 3 hours. The reaction solution is evaporated down using a rotary evaporator and the residue is chromatographed on a silica gel column with cyclohexane/ethyl acetate (1:1).

Workup

  1. customThe reaction solution is evaporated down
  2. customa rotary evaporator
  3. customthe residue is chromatographed on a silica gel column with cyclohexane/ethyl acetate (1:1)

Sources & evidence

ORD record
ord-69a55bcf218c4d61aac4ab766d923252
Source dataset
uspto-grants-1991_11
Patent number
US05068334

Reaction notes

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