HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropanol → 2-Amino-6-(3-(3-thienyl)allyl)-4,5,7,8-tetrahydro-6H-thiazolo[5,4-d]azepin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropanol | HCID 3776 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-Amino-4,5,6,7,8-pentahydrothiazolo[5,4-d]azepine | HCID 19985785 | — |
| Reactant | 3-(3-Thienyl)allyl chloride | HCID 53648336 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 2-Amino-6-(3-(3-thienyl)allyl)-4,5,7,8-tetrahydro-6H-thiazolo[5,4-d]azepin | HCID 54341373 | 8% |
Reaction Steps
Prepared from 3-(3-thienyl)allyl chloride and 1 equivalent of 2-amino-4,5,7,8-tetrahydro-6H- thiazolo[5,4-d]azepine in chloroform in the presence of I equivalent of potassium carbonate. Yield: 8% of theory, Melting point: 128°-132° C. (isopropanol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05068325 |
| Source dataset | uspto-grants-1991_11 |
| ORD ID | ord-7c9c457a1d36436b9b7efbb9b46a2fb9 |
| Source note | uspto-grants-1991_11 |