HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl Ether → 2-Amino-6-(3-(3-nitro-phenyl)allyl)-4,5,7,8-tetrahydro-6H-thiazolo[5,4-d]azepine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | 1-(3-Chloro-propenyl)-3-nitro-benzene | HCID 4377749 | — |
| Reactant | 2-Amino-4,5,6,7,8-pentahydrothiazolo[5,4-d]azepine | HCID 19985785 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 2-Amino-6-(3-(3-nitro-phenyl)allyl)-4,5,7,8-tetrahydro-6H-thiazolo[5,4-d]azepine | HCID 54107459 | 56% |
Reaction Steps
Prepared from 3-nitro-cinnamyl chloride and 2 equivalents of 2-amino-4,5,7,8-tetrahydro-6H- thiazolo[5,4-d]azepine in chloroform. Yield: 56% of theory, Melting point: 165°-168° C. (ether).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05068325 |
| Source dataset | uspto-grants-1991_11 |
| ORD ID | ord-4d8b45506f654edab79e32f8d64a7226 |
| Source note | uspto-grants-1991_11 |