Diethyl Ether → HCID 54397091, compound

HRID 974298Notes

Reaction equation

HRID 974298 reaction equation
[CH3:1][O:2][C:3]1[C:12]([O:13][CH3:14])=[CH:11][CH:10]=[CH:9][C:4]=1[CH:5]=[CH:6][CH2:7]Cl.[NH2:15][C:16]1[S:17][C:18]2[CH2:19][CH2:20][NH:21][CH2:22][CH2:23][C:24]=2[N:25]=1.CCOCC>C(Cl)(Cl)Cl>[NH2:15][C:16]1[S:17][C:18]2[CH2:19][CH2:20][N:21]([CH2:7][CH:6]=[CH:5][C:4]3[CH:9]=[CH:10][CH:11]=[C:12]([O:13][CH3:14])[C:3]=3[O:2][CH3:1])[CH2:22][CH2:23][C:24]=2[N:25]=1

Participants

5

Reactant 3

HCID 3283Diethyl EtherHCID 199857852-Amino-4,5,6,7,8-pentahydrothiazolo[5,4-d]azepineHCID 53706219HCID 53706219, compound

Product 1

HCID 54397091HCID 54397091, compoundYield 39%

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

Prepared from 2,3-dimethoxy-cinnamyl chloride and 2 equivalents of 2-amino-4,5,7,8-tetrahydro-6H-thiazolo[5,4-d]azepine in chloroform. Yield: 39% of theory, Melting point: 87°-9 1° C. (ether).

Sources & evidence

ORD record
ord-993dece24cf849b1a3f5e882718b9ad1
Source dataset
uspto-grants-1991_11
Patent number
US05068325

Reaction notes

Loading…