2-Amino-4,5,6,7,8-pentahydrothiazolo[5,4-d]azepine → HCID 73668872, compound

HRID 974303Notes

Reaction equation

HRID 974303 reaction equation
[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[CH:11]=[CH:12][CH2:13]Cl.[NH2:15][C:16]1[S:17][C:18]2[CH2:19][CH2:20][NH:21][CH2:22][CH2:23][C:24]=2[N:25]=1>C(Cl)(Cl)Cl>[NH2:15][C:16]1[S:17][C:18]2[CH2:19][CH2:20][N:21]([CH2:13][CH:12]=[CH:11][C:2]3[CH:3]=[CH:4][C:5]4[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=4)[CH:1]=3)[CH2:22][CH2:23][C:24]=2[N:25]=1

Participants

4

Reactant 2

HCID 199857852-Amino-4,5,6,7,8-pentahydrothiazolo[5,4-d]azepineHCID 54182686HCID 54182686, compound

Product 1

HCID 73668872HCID 73668872, compoundYield 20%

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent2×

Procedure

Prepared from 3-(2-naphthyl)allyl chloride and 2 equivalents of 2-amino-4,5,7,8-tetrahydro-6 H-thiazolo[5,4-d]azepine in chloroform for 3 days at 20° C. Yield: 20% of theory, Melting point: 164°-165° C. (chloroform).

Sources & evidence

ORD record
ord-6eb2314c93ea41e6a35a7027b07c57bb
Source dataset
uspto-grants-1991_11
Patent number
US05068325

Reaction notes

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